Teaching Duties: Physiology, Principles of Biology, Neuroscience
Research Interests: My research focuses around 2 aspects related to the
control of blood pressure and mechanisms that contribute to the development
of hypertension. First, I am interested in how salt exacerbates hypertension
in certain individuals. My research has examined a number of areas related to
this topic, including how the brain detects sodium ingestion. We have demonstrated
that receptors in the liver respond to salt intake and send signals to the brain,
which in turn responds to decrease sodium appetite and prevent changes in plasma
sodium levels. Current work in my laboratory is expanding on this research,
and investigating the role of hepatic membrane phospholipids in regulating vascular
reactivity. My second area of interest revolves around the ability of estrogen
to protect individuals from hypertension and associated changes to the vasculature.
One branch of research in my laboratory is investigating whether estrogen depletion
increases the risk of hypertension and vascular complications in diabetic rat
models. Another set of studies are exploring whether estrogen depletion accelerates
hypertension-induced declines in cognitive function. All of these studies are
funded by external grants from the National Science Foundation, National Institutes
of Health, and the American Heart Association.
All of my research incorporates
undergraduate students who are interested in exploring physiological research,
either as a potential career, as preparation for professional school, or simply
have an interest in trying it out. Students participate in all aspects of the
research, including surgical preparations, data collection and analysis, and
presentation of research results. Additionally, students learn state-of-the-art
technologies, such as telemetric recording, Doppler flow probe monitoring and
vascular reactivity studies, which are techniques usually not available at the
undergraduate level. I am always looking for students who express an interest
in working in my laboratory. Hobbies: I have a great
wife and 2 kids, including a 5 year-old daughter and a 2 year-old son. We also
have a 3rd child who is currently under construction. Most of my time is spent
working to restore our 139 year-old house. I also enjoy landscaping, music,
and a variety of sports.
Revised April 2007